BDBM50658484 CHEMBL6166760

SMILES CS(=O)(=O)n1ccc(C(=O)NCC(=O)Nc2nc(-c3cccc(-c4ccncc4)c3)cs2)c1

InChI Key InChIKey=JETBPGYKVVHQEO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50658484   

TargetTranscription activator BRG1(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658484BDBM50658484(CHEMBL6166760)
Affinity DataIC50: 4nMAssay Description:Inhibition of C-terminal his6/FLAG-tagged BRG1 (unknown origin) (1 to 1647 residues) incubated for 2 hrs by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProbable global transcription activator SNF2L2(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658484BDBM50658484(CHEMBL6166760)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged BRM (unknown origin) (1 to 1590 residues) incubated for 2 hrs by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTranscription activator BRG1(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658484BDBM50658484(CHEMBL6166760)
Affinity DataIC50: 30nMAssay Description:Inhibition of BRG1 in human MDA-MB-231 cells co-transfected with MMTV incubated for 6 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProbable global transcription activator SNF2L2(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658484BDBM50658484(CHEMBL6166760)
Affinity DataIC50: 110nMAssay Description:Inhibition of BRM in human A549 cells co-transfected with MMTV incubated for 6 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetChromodomain-helicase-DNA-binding protein 4(Homo sapiens)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658484BDBM50658484(CHEMBL6166760)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of N-terminal FLAG-tagged,C-terminal his6-tagged CHD4 (unknown origin) (1 to 1912 residues) incubated for 1 hr by ADP-glo reagent based as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed