BDBM50661220 CHEMBL6145351

SMILES NS(=O)(=O)c1ccc(/N=C2S/C(=C3C(=O)Nc4ccc(Br)cc43)C(=O)N2C2CC2)cc1

InChI Key InChIKey=MIMGIDPGUZKVJN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50661220   

TargetCarbonic anhydrase 9(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661220BDBM50661220(CHEMBL6145351)
Affinity DataKi:  90nMAssay Description:Inhibition of recombinant human Carbonic anhydrase IX catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hydr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661220BDBM50661220(CHEMBL6145351)
Affinity DataKi:  199nMAssay Description:Inhibition of recombinant human Carbonic anhydrase II catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hydr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661220BDBM50661220(CHEMBL6145351)
Affinity DataKi:  240nMAssay Description:Inhibition of recombinant human Carbonic anhydrase XII catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661220BDBM50661220(CHEMBL6145351)
Affinity DataKi:  3.87E+3nMAssay Description:Inhibition of recombinant human Carbonic anhydrase I catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hydra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed