BDBM50664926 CHEMBL6174561

SMILES Cc1ccc(NC(=O)CN2C(=O)/C(=NNC(=O)c3cc(Br)ccc3O)c3ccc(Br)cc32)cc1

InChI Key InChIKey=LTTUZELADGWFLZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50664926   

TargetSmoothened homolog(Human)
University of Campania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664926BDBM50664926(CHEMBL6174561)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-cyclopamine from SMO receptor (unknown origin) expressed in HEK293T cell membranes measured after 4 hrs by liquid scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Campania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664926BDBM50664926(CHEMBL6174561)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human N-terminal GST-fused MET cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression system measured after 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed