BDBM50666115 CHEMBL6177732
SMILES O=Cc1cc(S(=O)(=O)NC(=O)c2cc(C(=O)O)ccn2)c2ccccc2c1O
InChI Key InChIKey=LKMAIUASYOEMFS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50666115
Affinity DataIC50: 170nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate assessed as ...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataKd: 560nMAssay Description:Binding affinity to ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant i...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataKd: 650nMAssay Description:Binding affinity to ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant i...More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.03E+3nMAssay Description:Binding affinity to ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant i...More data for this Ligand-Target Pair
Affinity DataKd: 1.14E+3nMAssay Description:Binding affinity to ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate measured imm...More data for this Ligand-Target Pair
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate incubated fo...More data for this Ligand-Target Pair
Affinity DataKd: 2.63E+3nMAssay Description:Binding affinity to ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant i...More data for this Ligand-Target Pair
Affinity DataKd: 2.80E+3nMAssay Description:Binding affinity to ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant b...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of ALKBH3 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of FTO (32 to 505 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of FTO (32 to 505 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells using m6A ssDNA as substrate incubated for 2...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 2.76E+4nMAssay Description:Binding affinity to FTO (32 to 505 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant by I...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.54E+4nMAssay Description:Inhibition of ALKBH3 (unknown origin) by restriction enzyme digestion methodMore data for this Ligand-Target Pair