BDBM50666630 CHEMBL6175985

SMILES O=C(Nc1cnc2ccccc2c1)c1cc2[nH]ccc2cc1Cl

InChI Key InChIKey=ZJPUSKBFLQMYJU-UHFFFAOYSA-N

Data  1 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50666630   

TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataEC50:  14nMAssay Description:Agonist activity at Gal4-fused human full length Nurr1 heterodimer transfected in HEK293T cells cotransfected with pFR-Luc-DR5 incubated for 16 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataEC50:  27nMAssay Description:Agonist activity at Gal4-fused human full length Nurr1 homodimer transfected in HEK293T cells cotransfected with pFR-Luc-NurRE incubated for 16 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 1(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataEC50:  40nMAssay Description:Agonist activity at Gal4-fused human Nur77 receptor expressed in HEK293T cells co-transfected with pFR-Luc and pRL-SV40 incubated for 16 hrs by firef...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataEC50:  60nMAssay Description:Agonist activity at Gal4-fused human Nurr1 LBD transfected in HEK293T cells cotransfected with pFR-Luc and pRL-SV40 incubated for 16 hrs by firefly/r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataEC50:  70nMAssay Description:Agonist activity at Gal4-fused human full length Nurr1 monomer transfected in HEK293T cells cotransfected with pFR-Luc-NBRE incubated for 16 hrs by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataEC50:  110nMAssay Description:Agonist activity at Gal4-fused full length human Nurr1 C566S mutant transfected in HEK293T cells cotransfected with pFR-Luc and pRL-SV40 incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-Universite

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666630BDBM50666630(CHEMBL6175985)
Affinity DataKd:  120nMAssay Description:Binding affinity to recombinant N-terminal 6His-tagged Nurr1 LBD (362 to 598 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3)-R3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed