BDBM50668168 CHEMBL6190456

SMILES CCC(CNC(=O)c1sc2cc(Br)c(OC)cc2c1F)C(=O)O

InChI Key InChIKey=IKUCDULXARUBTQ-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50668168   

TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668168BDBM50668168(CHEMBL6190456)
Affinity DataEC50:  1.32E+4nMAssay Description:Agonist activity at human STING HAQ variant in human THP1-Blue ISG cells assessed as fold change in stimulation activity measured after 24 hrs incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668168BDBM50668168(CHEMBL6190456)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to wild type His-tagged STING (unknown origin) measured after 3 hrs incubation by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668168BDBM50668168(CHEMBL6190456)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in human THP1-Dual cells assessed as fold change in stimulation activity measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668168BDBM50668168(CHEMBL6190456)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse STING expressed in human THP1-Dual cells assessed as fold change in stimulation activity measured after 24 hrs incubation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed