BDBM50668561 CHEMBL6192952

SMILES C[C@@H]1Sc2ccc(C(=O)NCc3cc4ccccc4o3)cc2-n2c(-c3ccc(F)cc3)nnc21

InChI Key InChIKey=JPIVGCXTBICJPR-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50668561   

TargetStimulator of interferon genes protein(Human)
Curadev Pharma Pvt. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668561BDBM50668561(CHEMBL6192952)
Affinity DataEC50:  51nMAssay Description:Activation of human STING HAQ variant transfected in HEK293T cells expressing ISRE.ISG54 luciferase reporter incubated for 20 hrs by luminometerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Curadev Pharma Pvt. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668561BDBM50668561(CHEMBL6192952)
Affinity DataEC50:  56nMAssay Description:Activation of human STING R232 variant transfected in HEK293T cells expressing ISRE.ISG54 luciferase reporter assessed as secretory reporter gene act...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Curadev Pharma Pvt. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668561BDBM50668561(CHEMBL6192952)
Affinity DataEC50:  89nMAssay Description:Activation of human STING H232 variant transfected in HEK293T cells expressing ISRE.ISG54 luciferase reporter incubated for 20 hrs by luminometerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Curadev Pharma Pvt. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668561BDBM50668561(CHEMBL6192952)
Affinity DataEC50:  218nMAssay Description:Activation of STING in human PBMC cells assessed as IFNbeta release incubated for 6 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Curadev Pharma Pvt. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668561BDBM50668561(CHEMBL6192952)
Affinity DataEC50:  372nMAssay Description:Activation of human STING HAQ variant transfected in human THP-1 cells expressing ISRE.ISG54 luciferase reporter incubated for 18 hrs by luminometerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed