BDBM50668781 CHEMBL6191979

SMILES Cc1nc(-c2cc(F)c(F)c(O)c2F)sc1C(=O)N(Cc1ccc(Cl)cc1)C(C)C

InChI Key InChIKey=SUCVDKDCOZRWKY-UHFFFAOYSA-N

Data  8 IC50  1 Kd  15 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50668781   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HSD17B13 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataKd:  19nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 55nMAssay Description:Inhibition of mouse HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ER alpha (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ER beta (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at LXRalpha (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetOxysterols receptor LXR-beta(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at LXRbeta (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPAR gamma expressed in HEK293 cells incubated for 18 hrs by FLIPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RXR alpha (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor alpha(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RAR alpha (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor gamma(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RAR gamma (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSD17B2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSD17B11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSD17B14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GR (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProgesterone receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at AR (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVitamin D3 receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at VDR (unknown origin) transfected in African green monkey CV-1 cells using luciferase as substrate incubated for 18 hrs by lucifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFatty acid-binding protein, liver(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FABP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FABP4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPAR alpha expressed in HEK293 cells incubated for 18 hrs by FLIPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668781BDBM50668781(CHEMBL6191979)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPAR delta expressed in HEK293 cells incubated for 18 hrs by FLIPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed