BDBM50531256 CHEMBL520726::NSC-382025

SMILES CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)[C@@](C)(C(=O)O)[C@@H]5CC[C@]43C)[C@@H]2C1

InChI Key InChIKey=IDGXIXSKISLYAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531256   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531256BDBM50531256(CHEMBL520726 | NSC-382025)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531256BDBM50531256(CHEMBL520726 | NSC-382025)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531256BDBM50531256(CHEMBL520726 | NSC-382025)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531256BDBM50531256(CHEMBL520726 | NSC-382025)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed