BDBM50646150 CHEMBL5583913::US12534451, Compound PZ-3022

SMILES c1cc(ccc1CC(=O)N2CCN(CC2)c3ccc(nn3)C#N)C4CC4

InChI Key InChIKey=CXSADKGUEBUMLH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50646150   

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646150BDBM50646150(CHEMBL5583913 | US12534451, Compound PZ-3022)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646150BDBM50646150(CHEMBL5583913 | US12534451, Compound PZ-3022)
Affinity DataIC50: 6.80nMAssay Description:PANK activity assay was performed in the presence of 0-10 μM compound in a reaction mixture that contained 100 mM Tris-HCl, pH 7.5, 10 mM MgCl2, 2.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)