Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50023545
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664960BDBM50664960(CHEMBL6175959)
Affinity DataKi:  0.130nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664961BDBM50664961(CHEMBL6169753)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664961BDBM50664961(CHEMBL6169753)
Affinity DataKi:  0.150nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664954BDBM50664954(CHEMBL6161530)
Affinity DataKi:  0.200nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664960BDBM50664960(CHEMBL6175959)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664954BDBM50664954(CHEMBL6161530)
Affinity DataKi:  0.420nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664954BDBM50664954(CHEMBL6161530)
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664959BDBM50664959(CHEMBL6174212)
Affinity DataKi:  1.30nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664959BDBM50664959(CHEMBL6174212)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664954BDBM50664954(CHEMBL6161530)
Affinity DataKi:  2nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664962BDBM50664962(CHEMBL6164003)
Affinity DataKi:  2.5nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664958BDBM50664958(CHEMBL6163462)
Affinity DataKi:  5nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664957BDBM50664957(CHEMBL6151962)
Affinity DataKi:  5nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664962BDBM50664962(CHEMBL6164003)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664956BDBM50664956(CHEMBL6167239)
Affinity DataKi:  8nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463484BDBM50463484(CHEMBL4248525)
Affinity DataKi: >9nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664956BDBM50664956(CHEMBL6167239)
Affinity DataKi:  10nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664964BDBM50664964(CHEMBL6176850)
Affinity DataKi:  16nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664958BDBM50664958(CHEMBL6163462)
Affinity DataKi:  20nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664965BDBM50664965(CHEMBL6144161)
Affinity DataKi:  25nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664957BDBM50664957(CHEMBL6151962)
Affinity DataKi:  25nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664964BDBM50664964(CHEMBL6176850)
Affinity DataKi:  50nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664965BDBM50664965(CHEMBL6144161)
Affinity DataKi:  79nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664955BDBM50664955(CHEMBL6176284)
Affinity DataKi:  126nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664955BDBM50664955(CHEMBL6176284)
Affinity DataKi:  159nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664966BDBM50664966(CHEMBL6143508)
Affinity DataKi:  251nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664963BDBM50664963(CHEMBL6166868)
Affinity DataKi:  251nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664966BDBM50664966(CHEMBL6143508)
Affinity DataKi:  316nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664963BDBM50664963(CHEMBL6166868)
Affinity DataKi:  316nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed