Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50023370
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662598BDBM50662598(CHEMBL6168306)
Affinity DataIC50: 90nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662596BDBM50662596(CHEMBL6134397)
Affinity DataIC50: 130nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662599BDBM50662599(CHEMBL6168485)
Affinity DataIC50: 140nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662597BDBM50662597(CHEMBL6153000)
Affinity DataIC50: 180nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662585BDBM50662585(CHEMBL6173756)
Affinity DataIC50: 180nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662594BDBM50662594(CHEMBL6175731)
Affinity DataIC50: 210nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662582BDBM50662582(CHEMBL6143448)
Affinity DataIC50: 230nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662595BDBM50662595(CHEMBL6172468)
Affinity DataIC50: 230nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662589BDBM50662589(CHEMBL6166853)
Affinity DataIC50: 280nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662591BDBM50662591(CHEMBL6171276)
Affinity DataIC50: 330nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662583BDBM50662583(CHEMBL6163821)
Affinity DataIC50: 340nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662590BDBM50662590(CHEMBL6175590)
Affinity DataIC50: 450nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662588BDBM50662588(CHEMBL6145018)
Affinity DataIC50: 490nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662593BDBM50662593(CHEMBL6173407)
Affinity DataIC50: 630nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662592BDBM50662592(CHEMBL6177620)
Affinity DataIC50: 860nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662587BDBM50662587(CHEMBL6167057)
Affinity DataIC50: 860nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662586BDBM50662586(CHEMBL6165719)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Helmholtz Centre for Infection Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662584BDBM50662584(CHEMBL6161667)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in gyrase supercoiling preincubated for 15 mins followed by relaxed pBR322 plasmid ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed