Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50022960
TargetProtein arginine N-methyltransferase 5(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656775BDBM50656775(CHEMBL6103457)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656775BDBM50656775(CHEMBL6103457)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PRMT7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656775BDBM50656775(CHEMBL6103457)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178103BDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT6 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178103BDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PRMT1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446401BDBM50446401(CHEMBL3109656)
Affinity DataIC50: 150nMAssay Description:Inhibition of human PRMT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656778BDBM50656778(CHEMBL6161408)
Affinity DataIC50: 270nMAssay Description:Inhibition of His-tagged PRMT1 (unknown origin) extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648686BDBM50648686(CHEMBL5612079)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human PRMT1 assessed as methyltransferase activity using Histone H4 /H4 (1-15)-Biotin as substrate by radioisotope based MT HotSpot ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656773BDBM50656773(CHEMBL6150286)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant PRMT1 extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550091BDBM50550091(CHEMBL4648477)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of His-tagged human recombinant PRMT1 extracted from BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656776BDBM50656776(CHEMBL6163510)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544161BDBM50544161(CHEMBL4640122)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human PRMT1 assessed as methyltransferase activity using Histone H4 /H4 (1-15)-Biotin as substrate by radioisotope based MT HotSpot ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648705BDBM50648705(CHEMBL5613322)
Affinity DataIC50: 5.36E+3nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656771BDBM50656771(CHEMBL6150814)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of GST-tagged PRMT1 (unknown origin) using P3 as substrate measured for 90 mins by liquid scintillation methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015234BDBM50015234(CHEMBL25105 | 4,4''[1,6-HEXANEDIYLBIS(OXY)]BISBENZ...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of N-terminal 6His-tagged recombinant PRMT1 (unknown origin) extracted from Escherichia coli BL21 (DE3) cells by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656775BDBM50656775(CHEMBL6103457)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637547BDBM50637547(CHEMBL5558679)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of human PRMT1 assessed as methyltransferase activity using Histone H4 /H4 (1-15)-Biotin as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637546BDBM50637546(CHEMBL5563346)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of human PRMT1 assessed as methyltransferase activity using Histone H4 /H4 (1-15)-Biotin as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656773BDBM50656773(CHEMBL6150286)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of His-tagged human recombinant PRMT6 extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648705BDBM50648705(CHEMBL5613322)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PRMT6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346719BDBM50346719(CHEMBL1269351)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 45440BDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of N-terminal 6His-tagged recombinant PRMT1 (unknown origin) extracted from Escherichia coli BL21 (DE3) cells by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597857BDBM50597857(CHEMBL5181815)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of 6His-tagged PRMT1 (11 to 353 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656777BDBM50656777(CHEMBL1623478)
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of 6His-tagged PRMT1 (11 to 353 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656772BDBM50656772(CHEMBL6150543)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human recombinant PRMT1 extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656772BDBM50656772(CHEMBL6150543)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of His-tagged human recombinant PRMT3 extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656772BDBM50656772(CHEMBL6150543)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of His-tagged human recombinant PRMT6 extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656774BDBM50656774(CHEMBL6142747)
Affinity DataIC50: 3.96E+5nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656773BDBM50656773(CHEMBL6150286)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of His-tagged human recombinant PRMT3 extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed