Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50023728
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146428BDBM50146428((S)-1-((1R,5S)-5-Benzoylamino-2-methyl-4-oxo-6-phe...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398088BDBM50398088(CHEMBL2097001)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21642BDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ACE (unknown origin) using Hip-His-Leu-OH peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667383BDBM50667383(CHEMBL6193492)
Affinity DataKi:  10nMAssay Description:Binding affinity to ACE (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667382BDBM50667382(CHEMBL6190664)
Affinity DataIC50: 14nMAssay Description:Inhibition of ACE (unknown origin) using N-[3-(2-furyl)-acryloyl]- L -phenylalanylglycylglycin as substrate incubated for 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HDAC5 using Ac-Leu-Gly-Lys(Tfa)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HDAC6 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant full length HDAC3 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HDAC4 using Ac-Leu-Gly-Lys(Tfa)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant full length HDAC2 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667384BDBM50667384(CHEMBL6193619)
Affinity DataIC50: 43nMAssay Description:Inhibition of ACE (unknown origin) using Hip-His-Leu-OH peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124883BDBM50124883(CHEMBL3137700)
Affinity DataKi:  47nMAssay Description:Binding affinity to AChE (unknown origin) using acetylthiocholine iodide as substrate assessed as inhibition constant by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667396BDBM50667396(CHEMBL6189555)
Affinity DataIC50: 113nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667397BDBM50667397(CHEMBL6192506)
Affinity DataIC50: 113nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667398BDBM50667398(CHEMBL6192606)
Affinity DataIC50: 113nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667388BDBM50667388(CHEMBL6188892)
Affinity DataEC50:  250nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462118BDBM50462118(CHEMBL4243296)
Affinity DataKi:  300nMAssay Description:Binding affinity to guinea pig sigma 1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462120BDBM50462120(CHEMBL4243361)
Affinity DataKi:  300nMAssay Description:Binding affinity to guinea pig sigma 1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462119BDBM50462119(CHEMBL4247145)
Affinity DataKi:  300nMAssay Description:Binding affinity to guinea pig sigma 1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667395BDBM50667395(CHEMBL6190124)
Affinity DataKi:  300nMAssay Description:Binding affinity to guinea pig sigma 1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667389BDBM50667389(CHEMBL6190195)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667390BDBM50667390(CHEMBL6189165)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667391BDBM50667391(CHEMBL6189008)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667392BDBM50667392(CHEMBL6190417)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667393BDBM50667393(CHEMBL6189988)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667394BDBM50667394(CHEMBL6190345)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462116BDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC4 using Ac-Leu-Gly-Lys(Tfa)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462116BDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC5 using Ac-Leu-Gly-Lys(Tfa)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462116BDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant full length HDAC2 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462116BDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant full length HDAC3 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462116BDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462116BDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC6 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 30 mins by EnSpire plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667387BDBM50667387(CHEMBL6193583)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667385BDBM50667385(CHEMBL6191466)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667386BDBM50667386(CHEMBL6189526)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Rat)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462127BDBM50462127(CHEMBL4239086)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at rat GPR109A transfected in T-REX-CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146431BDBM50146431((S)-1-{3-[(1-Benzoylamino-3-methyl-butyl)-dihydrox...)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of ACE (unknown origin) using N-[3-(2-furyl)-acryloyl]- L -phenylalanylglycylglycin as substrate incubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific and Industrial Research (CSIR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667381BDBM50667381(CHEMBL6191946)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed