Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50023388
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Displacement of [3H]SB-674042 from recombinant human OX1R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]SB-674042 from recombinant human OX1R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Displacement of [3H]SB-674042 from recombinant human OX1R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]EMPA from recombinant human OX2R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]EMPA from recombinant human OX2R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [3H]EMPA from recombinant human OX2R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataKi: 156nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 253nMAssay Description:Displacement of [125I]Orexin A from recombinant human OX1R expressed in CHO-S cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of [125I]Orexin A from recombinant human OX2R expressed in CHO-S cells by radioligand competition binding assayMore data for this Ligand-Target Pair
