Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50022876
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655501BDBM50655501(CHEMBL6147832)
Affinity DataKi:  0.110nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578692BDBM50578692(CHEMBL4877950)
Affinity DataKi:  0.190nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578692BDBM50578692(CHEMBL4877950)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655501BDBM50655501(CHEMBL6147832)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655504BDBM50655504(Cefditoren pivoxil | Cefditoren pivaloyloxymethyl ...)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655502BDBM50655502(CHEMBL6133145)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655503BDBM50655503(CHEMBL3184257)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248359BDBM50248359(Adefovir dipivoxil | GS-0840 | Hepsera)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655502BDBM50655502(CHEMBL6133145)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655503BDBM50655503(CHEMBL3184257)
Affinity DataKi:  120nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655504BDBM50655504(Cefditoren pivoxil | Cefditoren pivaloyloxymethyl ...)
Affinity DataKi:  150nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248359BDBM50248359(Adefovir dipivoxil | GS-0840 | Hepsera)
Affinity DataKi:  170nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228403BDBM50228403(8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-m...)
Affinity DataKi:  340nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359366BDBM50359366(CHEMBL1929387 | CHEMBL1929396 | US20240115577, Com...)
Affinity DataKi:  380nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228403BDBM50228403(8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-m...)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084637BDBM50084637(Sivelestat | 2,2-Dimethyl-propionic acid 4-[2-(car...)
Affinity DataKi:  590nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655505BDBM50655505(Tebipenem pivoxil | Tebipenem pivoxilo | L-084 | L...)
Affinity DataKi:  640nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120433BDBM50120433(ONO-5046.NA | Sivelestat Sodium)
Affinity DataKi:  730nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 77145BDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataKi:  890nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084637BDBM50084637(Sivelestat | 2,2-Dimethyl-propionic acid 4-[2-(car...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 77145BDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 77145BDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359366BDBM50359366(CHEMBL1929387 | CHEMBL1929396 | US20240115577, Com...)
Affinity DataIC50: 7.27E+4nMAssay Description:Inhibition of FAP (unknown origin) activity extracted from baculovirus-infected Sf9 cells assessed as degradation of Ala-Pro-7-amino-3-trifluoromethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655507BDBM50655507(Cefetamet | Cefetamet pivoxil hydrochloride | Deac...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655506BDBM50655506(CHEMBL6145714)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450813BDBM50450813(CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001103BDBM50001103(9-[2-phosphonomethoxyethyl]adenine | 9-(2-(phospho...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359366BDBM50359366(CHEMBL1929387 | CHEMBL1929396 | US20240115577, Com...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed