Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50022881
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 3nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 3nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655576BDBM50655576(CHEMBL6151902)
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 177922BDBM177922(US9675614, 166 | US10307413, Compound 337 | US1039...)
Affinity DataIC50: 22nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate preincubated with compound for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655551BDBM50655551(CHEMBL6160606)
Affinity DataIC50: 22nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655567BDBM50655567(CHEMBL6142622)
Affinity DataIC50: 28nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655568BDBM50655568(CHEMBL6142322)
Affinity DataIC50: 31nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655561BDBM50655561(CHEMBL6146986)
Affinity DataIC50: 34nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655558BDBM50655558(CHEMBL6160119)
Affinity DataIC50: 40nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655572BDBM50655572(CHEMBL6142233)
Affinity DataIC50: 42nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655553BDBM50655553(CHEMBL6163664)
Affinity DataIC50: 43nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655557BDBM50655557(CHEMBL6147288)
Affinity DataIC50: 46nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655559BDBM50655559(CHEMBL6147031)
Affinity DataIC50: 47nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655570BDBM50655570(CHEMBL6164100)
Affinity DataIC50: 47nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655556BDBM50655556(CHEMBL6161169)
Affinity DataIC50: 48nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655552BDBM50655552(CHEMBL6150306)
Affinity DataIC50: 49nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655555BDBM50655555(CHEMBL6162783)
Affinity DataIC50: 50nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655569BDBM50655569(CHEMBL6102896)
Affinity DataIC50: 57nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655560BDBM50655560(CHEMBL6146724)
Affinity DataIC50: 58nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655571BDBM50655571(CHEMBL6133650)
Affinity DataIC50: 63nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462572BDBM50462572(CHEMBL4249337)
Affinity DataIC50: 66nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655566BDBM50655566(CHEMBL6145545)
Affinity DataIC50: 80nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655575BDBM50655575(CHEMBL6120456)
Affinity DataIC50: 86nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655563BDBM50655563(CHEMBL6150800)
Affinity DataIC50: 87nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655564BDBM50655564(CHEMBL6142406)
Affinity DataIC50: 90nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655565BDBM50655565(CHEMBL6133209)
Affinity DataIC50: 100nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655573BDBM50655573(CHEMBL6142702)
Affinity DataIC50: 170nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655554BDBM50655554(CHEMBL6101838)
Affinity DataIC50: 224nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655562BDBM50655562(CHEMBL6141795)
Affinity DataIC50: 294nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655574BDBM50655574(CHEMBL6120744)
Affinity DataIC50: 385nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655579BDBM50655579(CHEMBL6147530)
Affinity DataIC50: 437nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655580BDBM50655580(CHEMBL6144029)
Affinity DataIC50: 821nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655578BDBM50655578(CHEMBL6150584)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone H4/SAM as substrate incubated for 150 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GLP (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NSD3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PRMT8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of G9a (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EZH2 (unknown origin) preincubated with compound for 10 mins followed by peptide substrate/SAM addition and measured after 4 hrs by HTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655577BDBM50655577(CHEMBL6159898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NSD2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed