Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50023013
TargetWD repeat-containing protein 5(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657824BDBM50657824(CHEMBL6165372)
Affinity DataKd:  69nMAssay Description:Binding affinity to WDR5 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50164794BDBM50164794(CHEMBL3798846 | US11174250, Example Table4.1.1 | U...)
Affinity DataIC50: 70nMAssay Description:Competitive binding to N-terminally NL-tagged WDR5 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo as substrate incubated for 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657823BDBM50657823(CHEMBL6146338)
Affinity DataKd:  241nMAssay Description:Binding affinity to WDR5 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632541BDBM50632541(CHEMBL5412474)
Affinity DataKd:  490nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657824BDBM50657824(CHEMBL6165372)
Affinity DataKd:  1.00E+3nMAssay Description:Displacement of FITC-labeled [3H] (1 to 15 ) from WDR5 (unknown origin) assessed as dissociation constant incubated for 30 mins by fluorescence polar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657824BDBM50657824(CHEMBL6165372)
Affinity DataIC50: 1.70E+3nMAssay Description:Competitive binding to N-terminally NL-tagged WDR5 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo as substrate incubated for 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657830BDBM50657830(CHEMBL6146761)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to 15N-labeled DNMT3A PWWP domain (unknown origin) assessed as dissociation constant by NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657813BDBM50657813(CHEMBL6163762)
Affinity DataKd:  4.00E+3nMAssay Description:Competitive binding to SETDB1-TTD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657824BDBM50657824(CHEMBL6165372)
Affinity DataKd:  4.00E+3nMAssay Description:Displacement of FITC-labeled MILL-WIN from WDR5 (unknown origin) assessed as dissociation constant incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657827BDBM50657827(CHEMBL6165922)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to LRRK2 (unknown origin) assessed as dissociation constant by F-NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetRibosome biogenesis protein WDR12(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657826BDBM50657826(CHEMBL6145044)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to WDR12 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657821BDBM50657821(CHEMBL6134254)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632552BDBM50632552(CHEMBL5395769)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657816BDBM50657816(CHEMBL6132819)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657831BDBM50657831(CHEMBL6146700)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to 15N-labeled DNMT3A PWWP domain (unknown origin) assessed as dissociation constant by NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657828BDBM50657828(CHEMBL6161192)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to LRRK2 (unknown origin) assessed as dissociation constant by F-NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657833BDBM50657833(CHEMBL6151674)
Affinity DataKd:  1.20E+4nMAssay Description:Competitive binding to SETDB1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632553BDBM50632553(CHEMBL5396812)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657815BDBM50657815(CHEMBL6150013)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657814BDBM50657814(CHEMBL6164117)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657817BDBM50657817(CHEMBL6102472)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632550BDBM50632550(CHEMBL5413113)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657818BDBM50657818(CHEMBL6148496)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657819BDBM50657819(CHEMBL6120762)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetRibosome biogenesis protein WDR12(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657825BDBM50657825(CHEMBL6160759)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to WDR12 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657832BDBM50657832(CHEMBL6145854)
Affinity DataKd:  2.40E+4nMAssay Description:Competitive binding to SETDB1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657829BDBM50657829(CHEMBL6134222)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to LRRK2 (unknown origin) assessed as dissociation constant by F-NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657822BDBM50657822(CHEMBL6150824)
Affinity DataKd:  3.00E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632539BDBM50632539(CHEMBL5413155)
Affinity DataKd:  3.30E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657813BDBM50657813(CHEMBL6163762)
Affinity DataKd:  3.60E+4nMAssay Description:Displacement of FITC-labelled H3K9me2-K14Ac from SETDB1 (unknown origin) assessed as dissociation constant incubated for 30 mins by fluorescence pola...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632555BDBM50632555(CHEMBL5435870)
Affinity DataKd:  4.20E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657833BDBM50657833(CHEMBL6151674)
Affinity DataKd:  7.00E+4nMAssay Description:Competitive binding to SETDB1-TTD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDDB1- and CUL4-associated factor 1(Homo sapiens)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657820BDBM50657820(CHEMBL6147887)
Affinity DataKd:  8.30E+4nMAssay Description:Binding affinity to DCAF1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed