Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50023632
TargetProtein arginine N-methyltransferase 5(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666076BDBM50666076(CHEMBL6176251)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666069BDBM50666069(CHEMBL6175376)
Affinity DataIC50: 1nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666066BDBM50666066(CHEMBL6171882)
Affinity DataIC50: 2nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28422BDBM28422((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637558BDBM50637558(CHEMBL5523577)
Affinity DataIC50: 3nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636219BDBM50636219(CHEMBL5557446)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of CARM1 (unknown origin) using SAM as substrate pre-incubated with compound for 30 mins followed by substrate addition by top-count reade...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636219BDBM50636219(CHEMBL5557446)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate pre-incubated with compound for 30 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009672BDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PRMT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666067BDBM50666067(CHEMBL5612658)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 440444BDBM440444(US10633389, Example 109-3 | US20230279020, Example...)
Affinity DataIC50: 6nMAssay Description:Inhibition of FLAG-tagged CARM1 (2 to 585 residues) (unknown origin) extracted baculovirus infected Insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666067BDBM50666067(CHEMBL5612658)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PRMT1 using H4-21peptide as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50532879BDBM50532879(CHEMBL3347611)
Affinity DataIC50: 27nMAssay Description:Inhibition of human full length N-terminal CARM1 catalytic domain (134 to 483 residues) extracted from Insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609301BDBM50609301(CHEMBL4559961)
Affinity DataIC50: 43nMAssay Description:Inhibition of PRMT4 in HEK293 cells assessed as reduction in MED12 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666074BDBM50666074(CHEMBL6173741)
Affinity DataIC50: 43nMAssay Description:Inhibition of human N-terminal 6xHis-tagged CARM1 catalytic domain (140 to 480 residues) using histone H3 as substrate and SAM as cofactor by radiome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598000BDBM50598000(CHEMBL5209447)
Affinity DataIC50: 43nMAssay Description:Inhibition of human N-terminal 6xHis-tagged CARM1 catalytic domain (140 to 480 residues) using histone H3 as substrate and SAM as cofactor by radiome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666065BDBM50666065(CHEMBL6177857)
Affinity DataIC50: 60nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666071BDBM50666071(CHEMBL4062667)
Affinity DataIC50: 94nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666068BDBM50666068(CHEMBL5613157)
Affinity DataIC50: 138nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 6(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158094BDBM50158094(CHEMBL3780926)
Affinity DataIC50: 300nMAssay Description:Inhibition of PRMT6 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666067BDBM50666067(CHEMBL5612658)
Affinity DataIC50: 321nMAssay Description:Inhibition of human PRMT3 using H4-21peptide as substrate incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609301BDBM50609301(CHEMBL4559961)
Affinity DataIC50: 340nMAssay Description:Inhibition of PRMT4 in HEK293 cells assessed as reduction in BAF155 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666070BDBM50666070(CHEMBL4099850)
Affinity DataIC50: 471nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666065BDBM50666065(CHEMBL6177857)
Affinity DataIC50: 500nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666064BDBM50666064(CHEMBL6177809)
Affinity DataIC50: 780nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158094BDBM50158094(CHEMBL3780926)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666075BDBM50666075(CHEMBL6173159)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of C-terminal His-tagged human CARM1 catalytic domain (135 to 479 residues) extracted from Escherichia coli BL21 CodonPlus (DE3)-RIL cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597856BDBM50597856(CHEMBL5195877)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of C-terminal His-tagged human CARM1 catalytic domain (135 to 479 residues) extracted from Escherichia coli BL21 CodonPlus (DE3)-RIL cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609301BDBM50609301(CHEMBL4559961)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human PRMT6 catalytic domain (1 to 375 residues) using core histones as substrate and [3]SAM as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245957BDBM50245957(CHEMBL4101956)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CARM1 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666071BDBM50666071(CHEMBL4062667)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of PRMT6 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648699BDBM50648699(CHEMBL5612557)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human PRMT1 using H4-21peptide as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666070BDBM50666070(CHEMBL4099850)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of PRMT6 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666063BDBM50666063(CHEMBL6176422)
Affinity DataIC50: 7.23E+3nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609301BDBM50609301(CHEMBL4559961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PRMT1 catalytic domain (30 to 371 residues) using histone Histone H4 as substrate and SAM as cofactor by radiometric HotSpot assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61066BDBM61066(SMR000230206 | MLS000705942 | 14-benzoylacenaphtho...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CARM1 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666073BDBM50666073(CHEMBL6172115)
Affinity DataIC50: 4.22E+4nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) extracted form Escherichia coli BL21 (DE3) by MTase-Glo reagent based luminometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666072BDBM50666072(CHEMBL6176111)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed