Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50023392
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 144315BDBM144315(US8969336, 577 | US8969336, 547 | Gilteritinib | U...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using biotin-tagged TK substrate preincubated for 10 mins followed by substrate and ATP addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662979BDBM50662979(CHEMBL6175470)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using biotin-tagged TK substrate preincubated for 10 mins followed by substrate and ATP addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662977BDBM50662977(CHEMBL6143328)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using biotin-tagged TK substrate preincubated for 10 mins followed by substrate and ATP addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662981BDBM50662981(CHEMBL6173154)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using biotin-tagged TK substrate preincubated for 10 mins followed by substrate and ATP addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662978BDBM50662978(CHEMBL6161489)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using biotin-tagged TK substrate preincubated for 10 mins followed by substrate and ATP addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662980BDBM50662980(CHEMBL6166264)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using biotin-tagged TK substrate preincubated for 10 mins followed by substrate and ATP addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed