Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50022910
TargetTyrosine-protein kinase JAK3(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.594nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-biotin as substrate incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.827nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-biotin as substrate incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK1 (unknown origin) using TK-biotin as substrate incubated for 120 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-biotin as substrate incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 27nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-biotin as substrate incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 27nMAssay Description:Inhibition of TYK2 (unknown origin) using TK-biotin as substrate incubated for 120 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 173nMAssay Description:Inhibition of TYK2 (unknown origin) using TK-biotin as substrate incubated for 120 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 337nMAssay Description:Inhibition of JAK1 (unknown origin) using TK-biotin as substrate incubated for 120 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProcathepsin L(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human Cat L using f Z-Phe-Arg-AMC as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProcathepsin L(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656020BDBM50656020(CHEMBL6141743)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human Cat L using f Z-Phe-Arg-AMC as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed