Compile Data Set for Download or QSAR
Report error Found 123 Enz. Inhib. hit(s) with all data for entry = 50022934
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362846BDBM50362846(CHEMBL1940394)
Affinity DataIC50: 10nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321718BDBM50321718(2-(2,4-dimethoxyphenylimino)-7-hydroxy-N-(pyridin-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16452BDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16314BDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50394657BDBM50394657(CHEMBL270067)
Affinity DataIC50: 20nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656340BDBM50656340(Minalrestat | WAY-ARI-509)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321715BDBM50321715(2-(2,5-dimethoxyphenylimino)-7-hydroxy-N-(pyridin-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321716BDBM50321716(2-(3,4-dimethoxyphenylimino)-7-hydroxy-N-(6-methyl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375584BDBM50375584(CHEMBL429432)
Affinity DataIC50: 50nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16314BDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 50nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029207BDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 80nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 200221BDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)
Affinity DataIC50: 80nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16512BDBM16512((2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chrome...)
Affinity DataIC50: 80nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362841BDBM50362841(CHEMBL1940399)
Affinity DataIC50: 100nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103504BDBM50103504(Sulindac | CHEBI:9352 | Clinoril)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant AKR1B1 by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 230nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7461BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataIC50: 290nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241453BDBM50241453(gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant AKR1B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656341BDBM50656341(CHEMBL6133621)
Affinity DataIC50: 300nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540070BDBM50540070(CHEMBL366760)
Affinity DataIC50: 300nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236240BDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataIC50: 320nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103504BDBM50103504(Sulindac | CHEBI:9352 | Clinoril)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant AKR1B10More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656345BDBM50656345(CHEMBL6150275)
Affinity DataIC50: 370nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025405BDBM50025405(10,13-Dimethyl-tetradecahydro-cyclopenta[a]phenant...)
Affinity DataIC50: 390nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056938BDBM50056938(NSC-66209 | cid_72721 | CHEMBL175266 | 2,6,7-Trihy...)
Affinity DataIC50: 400nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375561BDBM50375561(CHEMBL407717)
Affinity DataIC50: 440nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656342BDBM50656342(CHEMBL6152189)
Affinity DataIC50: 450nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388495BDBM50388495(CHEMBL2057301)
Affinity DataIC50: 500nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321717BDBM50321717(7-hydroxy-2-(4-methoxyphenylimino)-N-(pyridin-2-yl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362835BDBM50362835(CHEMBL1940400)
Affinity DataIC50: 500nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042949BDBM50042949((E)-3-(3,4-Dihydroxy-phenyl)-1-(2,4-dihydroxy-phen...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant AKR1B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656348BDBM50656348(CHEMBL6103402)
Affinity DataIC50: 500nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19459BDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 550nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16312BDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 550nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656344BDBM50656344(CHEMBL4160626)
Affinity DataIC50: 570nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029207BDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 570nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175892BDBM50175892(Maslinicacid | 2alpha,3beta-dihydroxy-12-oleanen-2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15236BDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 610nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16452BDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 620nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656340BDBM50656340(Minalrestat | WAY-ARI-509)
Affinity DataIC50: 740nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656350BDBM50656350(CHEMBL6170828)
Affinity DataIC50: 760nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17636BDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human recombinant AKR1B10More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656346BDBM50656346(CHEMBL486954)
Affinity DataIC50: 780nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241827BDBM50241827(CHEMBL4071421)
Affinity DataIC50: 800nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656343BDBM50656343(CHEMBL376915)
Affinity DataIC50: 810nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656347BDBM50656347(CHEMBL6164391)
Affinity DataIC50: 810nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656349BDBM50656349(CHEMBL6160316)
Affinity DataIC50: 830nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346601BDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 900nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
Displayed 1 to 50 (of 123 total ) | Next | Last >>
Jump to: