Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50023055
Affinity DataKd: 14nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 77nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 184nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 484nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.47E+3nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKd: 4.18E+3nMAssay Description:Binding affinity to wildtype TTR (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKd: 9.00E+3nMAssay Description:Binding affinity to human thyroid hormone-beta receptor assessed as apparent dissociation constant by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of acid-mediated TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by sodium acetate buffer at pH 5.2 additio...More data for this Ligand-Target Pair
Affinity DataKd: 5.80E+4nMAssay Description:Binding affinity to human thyroid hormone-beta receptor assessed as apparent dissociation constant by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+5nMAssay Description:Binding affinity to human thyroid hormone-beta receptor assessed as apparent dissociation constant by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.90E+5nMAssay Description:Binding affinity to human thyroid hormone-beta receptor assessed as apparent dissociation constant by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair

3D Structure (crystal)











