Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50022940
TargetHistone deacetylase 6(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656400BDBM50656400(CHEMBL6133532)
Affinity DataIC50: 4nMAssay Description:Inhibition of human HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656398BDBM50656398(CHEMBL6196052)
Affinity DataIC50: 6nMAssay Description:Inhibition of human HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602361BDBM50602361(CHEMBL5206304)
Affinity DataIC50: 9nMAssay Description:Inhibition of human HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656399BDBM50656399(CHEMBL6103029)
Affinity DataIC50: 9nMAssay Description:Inhibition of human HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439674BDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656400BDBM50656400(CHEMBL6133532)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656399BDBM50656399(CHEMBL6103029)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656398BDBM50656398(CHEMBL6196052)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602361BDBM50602361(CHEMBL5206304)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656400BDBM50656400(CHEMBL6133532)
Affinity DataIC50: 143nMAssay Description:Inhibition of human HDAC2 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656399BDBM50656399(CHEMBL6103029)
Affinity DataIC50: 156nMAssay Description:Inhibition of human HDAC2 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439674BDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656398BDBM50656398(CHEMBL6196052)
Affinity DataIC50: 196nMAssay Description:Inhibition of human HDAC2 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 215nMAssay Description:Inhibition of human HDAC2 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602361BDBM50602361(CHEMBL5206304)
Affinity DataIC50: 274nMAssay Description:Inhibition of human HDAC2 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439674BDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 361nMAssay Description:Inhibition of human HDAC2 using ZMAL (Z-(Ac)Lys-AMC) as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656400BDBM50656400(CHEMBL6133532)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(Tfa)-AMC as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602361BDBM50602361(CHEMBL5206304)
Affinity DataIC50: 5.26E+3nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(Tfa)-AMC as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439674BDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 7.22E+3nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(Tfa)-AMC as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656398BDBM50656398(CHEMBL6196052)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(Tfa)-AMC as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Bonn institution

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656399BDBM50656399(CHEMBL6103029)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(Tfa)-AMC as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed