Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50023585
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataEC50:  1.10E+3nMAssay Description:Effect on etomidate-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataEC50:  1.30E+3nMAssay Description:Effect on R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA recept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395121BDBM50395121(CHEMBL2163548)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataEC50:  5.60E+3nMAssay Description:Effect on etomidate-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataEC50:  8.10E+3nMAssay Description:Effect on R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA recept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665455BDBM50665455(CHEMBL6173745)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665453BDBM50665453(CHEMBL6171250)
Affinity DataEC50:  2.20E+4nMAssay Description:Positive allosteric modulation on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665454BDBM50665454(CHEMBL6167393)
Affinity DataEC50:  3.20E+4nMAssay Description:Positive allosteric modulation on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665450BDBM50665450(CHEMBL6169538)
Affinity DataEC50:  3.20E+4nMAssay Description:Mixed effect on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor extracted f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor alpha-1/beta-3(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataIC50: 3.60E+4nMAssay Description:Effect on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3 GABAA receptor extracted from Tetracycline-resistant HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataIC50: 3.70E+4nMAssay Description:Competitive inhibition of [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665457BDBM50665457(CHEMBL6167413)
Affinity DataIC50: 3.70E+4nMAssay Description:Competitive inhibition of [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665454BDBM50665454(CHEMBL6167393)
Affinity DataEC50:  3.80E+4nMAssay Description:Positive allosteric modulation on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665450BDBM50665450(CHEMBL6169538)
Affinity DataIC50: 3.80E+4nMAssay Description:Mixed-type inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665456BDBM50665456(CHEMBL6176429)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665451BDBM50665451(CHEMBL6175098)
Affinity DataEC50:  1.07E+5nMAssay Description:Mixed effect on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor extracted f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665451BDBM50665451(CHEMBL6175098)
Affinity DataIC50: 1.12E+5nMAssay Description:Mixed-type inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665458BDBM50665458(CHEMBL6164372)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665452BDBM50665452(CHEMBL6165260)
Affinity DataIC50: 1.16E+5nMAssay Description:Mixed-type inhibition of R-mTFD-MPAB-induced [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGABA-A receptor; alpha-1/beta-3/gamma-2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665452BDBM50665452(CHEMBL6165260)
Affinity DataEC50: >3.00E+5nMAssay Description:Mixed effect on [3H]muscimol binding to full length human N-terminal flag-tagged alpha1-beta3-C-terminal 1D4-tagged gamma2 GABAA receptor extracted f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed