Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50023830
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668920BDBM50668920(CHEMBL6188807)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668920BDBM50668920(CHEMBL6188807)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MERTK (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625502BDBM50625502(Glesatinib | Mgcd-265 | MG-90265 | MG-90265X | MG9...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MERTK (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172078BDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MERTK (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of AXL (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625502BDBM50625502(Glesatinib | Mgcd-265 | MG-90265 | MG-90265X | MG9...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of AXL (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172078BDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of AXL (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of KDR (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625502BDBM50625502(Glesatinib | Mgcd-265 | MG-90265 | MG-90265X | MG9...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of KDR (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065457BDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172078BDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625502BDBM50625502(Glesatinib | Mgcd-265 | MG-90265 | MG-90265X | MG9...)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625502BDBM50625502(Glesatinib | Mgcd-265 | MG-90265 | MG-90265X | MG9...)
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172078BDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Mer(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 250nMAssay Description:Inhibition of MERTK (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 250nMAssay Description:Inhibition of AXL (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 250nMAssay Description:Inhibition of KDR (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172078BDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 341nMAssay Description:Inhibition of KDR (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065457BDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed