| Assay Method Information | |
| | ChEMBL_2646631 |
| Description: | Inhibition of His-tagged GDP-loaded KRAS G12C mutant (unknown origin) assessed as SOS1-mediated guanine nucleotide exchange preincubated with compound for 1 hrs followed by Flag-tagged SOS1 ExD and GTP addition and measured after 4 hrs by TR-FRET assay |
| Affinity data for this assay | |
|---|---|
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