BDBM50061565 (+)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine::(+/-)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine::(-)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine::CHEMBL267936::MECAMYLAMINE::Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine::Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine(Mecamylamine)

SMILES CNC1(C)C2CCC(C2)C1(C)C

InChI Key InChIKey=IMYZQPCYWPFTAG-UHFFFAOYSA-N

Data  21 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50061565   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi:  560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi:  1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed inhibition of epibatidine-induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Human)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi:  3.06E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50061565BDBM50061565(Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-a...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed